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The lab and the Serum

The Serum is made in four steps on four machines. Use a machine to open it: its screen lists every recipe it knows and what it is waiting for. Hoppers work too: ingredients go in from the top, fuel from the sides, and products come out of the bottom.

Screenshot cominglab-overview
A small lab: the four machines in a row, a chest and the Box behind them

The whole chain at a glance

➜Mortar Station➜
➜Mortar Station➜
➜Mortar Station➜
2
➜Centrifuge➜
➜Synthesizer➜
4
➜Cryo Stabilizer➜
4

Mortar Station

Grinds one item at a time, without fuel: a Somnium Cap into Somnium Powder, a Pale Lotus into Lotus Pulp, and a Quantum Shard into two Quantum Dust.

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Mortar Station (Crafting Table)

Centrifuge

Spins Lotus Pulp with a Water Bottle into Lotus Extract. It needs no fuel, and only plain water bottles will do: any other potion stops it.

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Centrifuge (Crafting Table)

Synthesizer

Combines Lotus Extract, Somnium Powder, Quantum Dust and a Phase Salt Crystal, in any order, into an Unstable Compound. It burns furnace fuel (coal, charcoal, wood, blaze rods, lava). If the fuel runs out mid-job, the job slowly cools back down and loses its progress.

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Synthesizer (Crafting Table)

Cryo Stabilizer

Fills four Hush Glass Ampoules from one Unstable Compound, making four Serum Ampoules. It only runs cold: packed ice or blue ice must touch one of its faces. Without cold a job pauses and keeps its progress.

A few worlds offer a coolant that stands in for ice. Use it on the Cryo Stabilizer to pour it in.

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Cryo Stabilizer (Crafting Table)
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Hush Glass Ampoule (Crafting Table)
Screenshot comingcryo-ice
A Cryo Stabilizer with a block of packed ice against its side, its screen open showing "Cold: ice touches the machine"

The Injector

You dose yourself with the Injector. It lasts 256 doses. See Crossing over.

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Injector (Crafting Table)

Better brews

Once you start bringing things back from other worlds, the Separator breaks them down into residues, and residues make stronger Serum.

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Separator (Crafting Table)
  • The Separator needs no fuel. Feed it anything from another world: 16 Common, 4 Uncommon or 1 Rare item make one residue, and a Signature item makes two. Each world gives the residue of its kind (the item's tooltip says which).
Brew How What it does
Refined Serum Ampoule Synthesizer: Unstable Compound + 2 Chronal Residue + Quantum Dust, then the Cryo Stabilizer as usual A dose that lasts 45 minutes instead of 20.
Return Ampoule Crafted: Serum Ampoule + Gravitic Residue + Mirror Residue While the Serum is running, folds you straight back to the Corridor door you came through.
Steady Draught Crafted: Serum Ampoule + 2 Serene Residue Cures Decoherence at once. It is not used up if there is nothing to cure.