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Gathering

Everything the Box and the Serum need is found in the ordinary Overworld and Nether, just not where you usually look. The Traveler's Guide opens its later chapters as you find each of these.

Tesseract

Tesseract Ore hides in deepslate, in small veins from the bottom of the world up to Y -16. You need an iron pickaxe or better. Smelt Raw Tesseract into Tesseract Ingots in a furnace or blast furnace.

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Tesseract Ore in a deepslate cave wall, lit by a torch

Galena (lead)

Galena sits in ordinary stone between Y 0 and Y 48 and needs a stone pickaxe. Smelt Raw Galena into Lead Ingots, then press two ingots side by side into two Lead Plates.

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Lead Plate (Crafting Table)

Hush Sand

Hush Sand lies in pockets in the deepslate and sculk of the Deep Dark. Smelt it into Hush Glass. Tread softly down there: the Warden lives in the same place.

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A pocket of Hush Sand among sculk in the Deep Dark

Quantum geodes

Quantum geodes form deep underground, below Y 30, and are rarer than amethyst geodes. Break the Quantum Clusters on their inner walls with a pickaxe for four Quantum Shards each (two with anything else). The Budding Superposition does not grow new clusters, so take every one you find.

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The inside of a quantum geode, glowing clusters on the walls

Phase Salt

Phase Salt Crust grows into the soul sand and soul soil of the Nether's Soul Sand Valleys. Each crust breaks into one to three Phase Salt Crystals.

Pale Lotus

The Pale Lotus grows along the shores of swamps and mangrove swamps. It opens only at night, and only an open flower can be picked: a closed one breaks into nothing. Go out after dark.

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Pale Lotus flowers open at night on a swamp shore

Somnium Cap

Somnium Caps are small mushrooms on the floor of dark forests.

Shopping list for a first trip

You need For
48 Tesseract Ingots, 48 Lead Plates, 12 Hush Glass The 95 Box Panels (12 crafts of 8)
2 Hush Glass, 2 Tesseract Ingots, 2 Lead Plates The Box Door
4 Quantum Shards, 2 Hush Glass, 1 Tesseract Ingot The Coherence Core
5 Tesseract Ingots, 11 Lead Plates, 5 Hush Glass, 2 Quantum Shards, plus some iron, redstone, smooth stone, packed ice and a furnace The four lab machines
1 Tesseract Ingot, 1 Hush Glass, 1 Quantum Shard The Injector
1 Somnium Cap, 1 Pale Lotus, 1 Quantum Shard, 1 Phase Salt Crystal, 3 Hush Glass, a water bottle and packed ice Each batch of 4 Serum Ampoules